Pathophysiology of chronic pancreatitis

Pathophysiology of gallstone pancreatitis.

Gallstone pancreatitis was first recognized as an entity by Opie in 1901 (1), and since then has generated volumes of literature which have attempted to explain its pathophysiology. Multiple animal experiments and human clinical studies in the past thirty years have led to a better understanding of both macro- and microscopic events which lead to pancreatic inflammation in the setting of a pass...

Pathophysiology of acute pancreatitis.

Acute pancreatitis is a common clinical condition. It is a disease of variable severity in which some patients experience mild, self-limited attacks while others manifest a severe, highly morbid, and frequently lethal attack. The exact mechanisms by which diverse etiological factors induce an attack are still unclear. It is generally believed that the earliest events in acute pancreatitis occur...

Pathophysiology of alcohol-induced pancreatitis.

Excessive ethanol consumption is a common risk factor for acute and chronic pancreatitis. Ethanol could lead to the onset of pancreatitis in a number of ways; the most recently discovered is its effect on intrapancreatic digestive enzyme activation, by either sensitizing acinar cells to pathologic stimuli or stimulating the release of a secretagogue (cholecystokinin) from duodenal I cells. Rece...

Pathophysiology of acute pancreatitis pdf

pancreatitis, and chronic pancreatitis

EDITORIAL SYNOPSIS Two hundred and five confirmed cases of pancreatitis have been classified. Primary calcifying pancreatitis is associated with alcoholism. Pancreatic changes are patchy and related to plugging of minute ducts. Cysts are frequent. Obstruction to the main pancreatic duct may also result in chronic pancreatitis. Acute pancreatitis and acute recurrent pancreatitis are often associ...